Chimeric Antigen Receptor Engineered T (CAR-T) Cells and Cancer Therapy
نویسنده
چکیده
Gene therapy has demonstrated significant potential as a cancer therapy in the last few years. The greatest successes have been reached by genetic modification of autologous patient T cells with chimeric antigen receptors (CARs), which are novel and synthetic receptors composed of the antigen-binding domain from a B cell receptor fused to the signaling elements associated with a T cell receptor [1].
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تاریخ انتشار 2016